Fig. 6. Effect of CXCL14 on 2DG6P accumulation. A,B) CXCL14 induced a concentration-dependent reduction in 2DG6P generation in MIN6 b-cells (A) and mouse islets (B). The glucose transporter inhibitor cytochalasin-B (Cyt, 50mM) also significantly reduced 2DG6P accumulation. Data are expressed as mean+SEM, n=6; *p<0.05, **p<0.01, ***p<0.001.